description Hugo Theorell Overview
Hugo Theorell was a Swedish biochemist who received the 1955 Nobel Prize in Physiology or Medicine for his groundbreaking research on oxidation enzymes. Working at the Karolinska Institute, he successfully isolated and characterized the active components of enzymes such as yellow cytochrome and alcohol dehydrogenase. His detailed studies significantly advanced the scientific understanding of how biological enzymes function at the molecular level.
help Hugo Theorell FAQ
What discovery made Hugo Theorell a Nobel laureate?
Theorell demonstrated key principles governing oxidation enzymes, including the relationship between an enzyme's protein portion and its active cofactor. That work earned him the 1955 Nobel Prize in Physiology or Medicine.
Which enzymes did Hugo Theorell study?
His research included flavoproteins such as the yellow enzyme as well as alcohol dehydrogenase and other oxidation-reduction enzymes. These systems helped reveal how cells transfer hydrogen and electrons during metabolism.
What did Theorell prove by separating and recombining yellow enzyme?
He showed that neither the isolated protein nor the flavin component had full catalytic activity alone. Recombining them restored the active enzyme, clarifying the role of cofactors in enzyme chemistry.
Is Hugo Theorell the same person as Axel Theorell?
Yes. His full name was Axel Hugo Theodor Theorell, and scientific accounts frequently shorten it to Hugo Theorell.
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