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M-Audio Oxygen Pro 49

8.8
Very Good
From ~$280 (One-time purchase)
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description M-Audio Oxygen Pro 49 Overview

The M-Audio Oxygen Pro 49 is a fantastic value-driven controller that offers features usually found in much more expensive units. It includes auto-mapping for major DAWs, a built-in arpeggiator, and a very capable keybed with aftertouch. The build quality is solid, and the layout is intuitive, making it a great choice for beginners who want a professional feature set without the high price tag. It is a reliable, all-around performer that handles everything from basic note entry to complex plugin control with ease.

recommend Best for: Ideal for home studio owners and performing musicians who need a portable, feature-rich controller with deep DAW integration but do not require weighted hammer-action keys.

info M-Audio Oxygen Pro 49 Specifications

balance M-Audio Oxygen Pro 49 Pros & Cons

thumb_up Pros
  • check Comprehensive DAW auto-mapping for Logic, Pro Tools, Cubase, and Ableton.
  • check 49 full-size keys with channel aftertouch, a feature rarely found in this price range.
  • check Built-in high-resolution arpeggiator with multiple modes and tap tempo.
  • check RGB-backlit pads and knobs for clear visual feedback in low-light studios.
  • check USB powered with optional 9V DC adapter for standalone MIDI use.
  • check Includes essential software (MPC Beats, Xpand!2) to get started immediately.
thumb_down Cons
  • close The chassis is constructed entirely of high-density plastic, feeling less robust than metal alternatives.
  • close Keys use a light synth-action mechanism, which lacks the weighted feel of a traditional piano.
  • close Limited tactile controls with only a single 70mm fader; users wanting more mixer control may be disappointed.
  • close Some high-end DAWs (like certain older versions) may require manual mapping adjustments for full compatibility.

help M-Audio Oxygen Pro 49 FAQ

Does the M-Audio Oxygen Pro 49 require drivers to work?

It is class-compliant, so it works as a standard MIDI controller without drivers on most operating systems. However, installing the M-Audio driver is recommended to unlock the full Auto-Mapping and firmware update features.

Can I use the sustain pedal from my old keyboard with this controller?

Yes, it features a standard 1/4" sustain pedal input. Most universal sustain pedals will work, but ensure it is a simple on/off switch type (not a continuous controller pedal) for standard operation.

Does this controller have semi-weighted or weighted keys?

The Oxygen Pro 49 uses a synth-action keybed with channel aftertouch. It is lighter and faster than semi-weighted keys, making it ideal for synth leads and fast playing, but not for simulating the weight of an acoustic piano.

Is it powered over USB or does it need an adapter?

It can be powered via the USB connection (bus power), making it highly portable. An optional 9V DC power adapter is available for users who prefer not to drain laptop power or need to power the device without a computer.

What is M-Audio Oxygen Pro 49?
The M-Audio Oxygen Pro 49 is a fantastic value-driven controller that offers features usually found in much more expensive units. It includes auto-mapping for major DAWs, a built-in arpeggiator, and a very capable keybed with aftertouch. The build quality is solid, and the layout is intuitive, making it a great choice for beginners who want a professional feature set without the high price tag. It is a reliable, all-around performer that handles everything from basic note entry to complex plugin control with ease.
How good is M-Audio Oxygen Pro 49?
M-Audio Oxygen Pro 49 scores 8.8/10 (Very Good) on Lunoo, making it a well-rated option in the MIDI Controller category. The M-Audio Oxygen Pro 49 earns an 8.8/10 for delivering premium performance at a mid-range price, highlighted by its responsive aftertouch keybed and...
How much does M-Audio Oxygen Pro 49 cost?
From ~$280 (One-time purchase). Visit the official website for the most up-to-date pricing.
What are the best alternatives to M-Audio Oxygen Pro 49?
What is M-Audio Oxygen Pro 49 best for?

Ideal for home studio owners and performing musicians who need a portable, feature-rich controller with deep DAW integration but do not require weighted hammer-action keys.

How does M-Audio Oxygen Pro 49 compare to Native Instruments Komplete Kontrol S61 MK3?
Is M-Audio Oxygen Pro 49 worth it in 2026?
With a score of 8.8/10, M-Audio Oxygen Pro 49 is highly rated in MIDI Controller. See all MIDI Controller ranked.
What are the key specifications of M-Audio Oxygen Pro 49?
  • Keys: 49 Full-Size, Synth-Action with Channel Aftertouch
  • Pads: 8 Velocity-Sensitive RGB Pads
  • Knobs: 8 360° Knobs
  • Power: USB Bus Power or 9V DC Adapter
  • Faders: 1 x 70mm Fader
  • Inputs: 2 x 1/4" (Sustain, Expression)

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