description George Snell Overview
George Snell (1903–1996) was an American geneticist who spent most of his career at the Jackson Laboratory in Bar Harbor, Maine. He shared the 1980 Nobel Prize in Physiology or Medicine with Jean Dausset and Baruj Benacerraf for discoveries concerning the genetic regulation of immune responses. Snell's research on inbred mouse strains led him to identify the major histocompatibility complex (MHC), which he called the H-2 complex, as the genetic determinant of tissue transplant acceptance or rejection. His findings laid the groundwork for understanding how the immune system distinguishes self from non-self.
help George Snell FAQ
At which laboratory did George Snell conduct his research?
George Snell spent the majority of his distinguished career at the Jackson Laboratory in Bar Harbor, Maine. His work there focused heavily on mouse genetics and immunology.
What key concept did George Snell discover to win the Nobel Prize?
Snell discovered the genetic factors that determine whether a transplanted tissue will be accepted or rejected by the recipient's body. These factors are known as the Major Histocompatibility Complex (MHC).
With whom did George Snell share the 1980 Nobel Prize?
He shared the 1980 Nobel Prize in Physiology or Medicine with Jean Dausset and Baruj Benacerraf. Together, their work established the genetic foundations governing the immune response.
When did George Snell live?
George Snell was born in 1903 and lived until 1996. He was an American geneticist whose pioneering work in the mid-20th century laid the groundwork for modern organ transplantation.
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