description Jean Dausset Overview
Jean Dausset (1916–2009) was a French immunologist who worked at the Hôpital Saint-Louis in Paris. He shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and George Snell for discoveries concerning genetically determined structures on the cell surface that regulate immune responses. Dausset identified the human leukocyte antigen (HLA) system, the human version of the major histocompatibility complex, demonstrating that these cell-surface molecules vary between individuals. His work enabled tissue compatibility testing that became essential for organ and bone marrow transplantation.
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Where did Jean Dausset conduct much of his immunological research?
Jean Dausset was a French immunologist who worked extensively at the Hôpital Saint-Louis in Paris. His clinical environment heavily influenced his research into human blood and tissue typing.
What was Jean Dausset's specific contribution to immunology?
Dausset discovered the human leukocyte antigen (HLA) system, which comprises the genetically determined structures on the surface of human cells. This system is essentially the human version of the Major Histocompatibility Complex (MHC).
With whom did Jean Dausset share the 1980 Nobel Prize?
Dausset shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and George Snell. Their combined research explained how the immune system distinguishes between the body's own cells and foreign invaders.
When did Jean Dausset live?
Jean Dausset was born in 1916 and passed away in 2009. He lived a long life that allowed him to see his discoveries applied to successful human organ transplantation and blood transfusions.
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