Top Results for Immunology

César Milstein (1927–2002) was an Argentine-British biochemist who spent his career at the MRC Laboratory of Molecular Biology in Cambridge, England. In 1975, together with Georges Köhler, he developed the hybridoma technique, which fuses antibody-producing B cells with immortal myeloma cells to gen...

Élie Metchnikoff (1845–1916) was a Russian-born zoologist and immunologist who discovered phagocytosis in 1882, observing that certain cells in starfish larvae engulf and destroy foreign particles. He termed these cells phagocytes and proposed they formed the basis of cellular immunity against infec...

Georges Köhler (1946–1995) was a German immunologist who, while working as a postdoctoral researcher at the MRC Laboratory of Molecular Biology in Cambridge, collaborated with César Milstein to develop the hybridoma technique in 1975. By fusing antibody-producing spleen cells from immunized mice wit...

Emil von Behring was a German physiologist and physician who developed serum therapy, fundamentally establishing the field of passive immunization. He is best known for discovering a diphtheria antitoxin, which significantly reduced childhood mortality from the disease, alongside a tetanus antitoxin...

Edward Jenner was an 18th-century English physician whose groundbreaking research established the principles of vaccination. He demonstrated immunity to smallpox by inoculating patients with cowpox material, a closely related virus. This pioneering work laid the foundation for modern immunology and...

Benjamin Rubin was an American inventor recognized for his significant contribution to public health. He developed the bifurcated vaccination needle in 1965, a device allowing simultaneous injection of vaccine and anesthetic into a single site. This innovation dramatically improved vaccination effic...

Rolf Zinkernagel is a Swiss immunologist whose collaborative work with Peter Doherty revealed how the immune system's T cells specifically recognize and destroy infected cells. They discovered that T cells must simultaneously recognize both the viral antigen and the host's own Major Histocompatibili...

Ralph Steinman was a Canadian immunologist who discovered dendritic cells, fundamentally altering the understanding of immune system activation. While studying cells in the mouse spleen in 1973, he identified these distinct cells and subsequently proved that they are the immune system's most effecti...

Peter Doherty is an Australian immunologist and veterinary surgeon whose research advanced the understanding of cell-mediated immunity. Working with Rolf Zinkernagel in the 1970s, he discovered that the immune system's T cells must recognize both the virus and a specific self-marker, known as the ma...

Bruce Beutler is an American immunologist and geneticist whose research clarified how the innate immune system detects and responds to infectious agents. He discovered that proteins called Toll-like receptors act as sensors, allowing immune cells to recognize molecules from bacteria and other pathog...

Jules A. Hoffmann is a French-Luxembourgish biologist who served as research director at the CNRS Institute of Molecular and Cellular Biology in Strasbourg and as president of the French Academy of Sciences. He shared the 2011 Nobel Prize in Physiology or Medicine with Bruce Beutler and Ralph Steinm...

Jean Dausset (1916–2009) was a French immunologist who worked at the Hôpital Saint-Louis in Paris. He shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and George Snell for discoveries concerning genetically determined structures on the cell surface that regulate immune res...

George Snell (1903–1996) was an American geneticist who spent most of his career at the Jackson Laboratory in Bar Harbor, Maine. He shared the 1980 Nobel Prize in Physiology or Medicine with Jean Dausset and Baruj Benacerraf for discoveries concerning the genetic regulation of immune responses. Snel...

Baruj Benacerraf was a Venezuelan-American immunologist whose research significantly advanced the understanding of the human immune system. He is best known for discovering the immune response (Ir) genes, which are located within the major histocompatibility complex (MHC) and determine an organism's...

Karl Landsteiner was an Austrian physician whose groundbreaking research revolutionized medicine. He identified and classified the four human blood groups – A, B, AB, and O – a discovery that enabled safe blood transfusions. This work earned him the Nobel Prize in Physiology or Medicine in 1930. His...

Paul Ehrlich was a German physician and researcher whose work profoundly shaped modern medicine. He pioneered chemotherapy with his development of Salvarsan, an effective treatment for syphilis, marking a significant shift in combating infectious diseases. His research into immunology, particularly...

The Encyclopedia of Immunology is a multi-volume reference work published by Academic Press that provides broad coverage of the immune system in health and disease. Organized alphabetically, the encyclopedia features peer-reviewed articles detailing the structure and function of immune cells, antibo...

Michael Heidelberger was an American biochemist and immunologist recognized as one of the founding figures of immunochemistry. Through rigorous laboratory analysis in the early 20th century, he demonstrated that antibodies are specialized proteins, moving the scientific understanding of the immune s...

John A. Mannick was a Boston University surgeon specializing in vascular surgery and immunology. His research significantly advanced knowledge regarding the body’s immune reaction to traumatic injuries. He investigated how the immune system responds during severe physical damage, contributing valuab...

The "Encyclopedia of Immunobiology" is a multi-volume scientific reference work published by Elsevier. It provides detailed overviews of the immune system, covering both innate and adaptive immunity across different organisms. The encyclopedia features peer-reviewed articles written by experts in th...

Anthony Fauci is an American physician and immunologist who directed the National Institute of Allergy and Infectious Diseases (NIAID) from 1984 to 2022. Born in Brooklyn, New York, in 1940, he graduated from Cornell University Medical College and joined the National Institutes of Health in 1968. He...

Drew Weissman is an American physician whose groundbreaking research revolutionized vaccine development. Working with Katalin Kariko, he pioneered the use of modified mRNA to create long-lasting and safer vaccines. His innovative approach addresses immune system challenges, primarily benefiting immu...

James Allison is an American immunologist recognized for his groundbreaking work on T cell receptors. His research fundamentally shifted cancer treatment strategies by demonstrating how to activate the body’s immune system to specifically target and destroy tumors. This approach has become a corners...

Tasuku Honjo is a Japanese immunologist recognized for his groundbreaking research into the regulation of the immune system. His work identified PD-1, an inhibitory receptor that acts as a crucial ‘brake’ on T cells, significantly impacting cancer immunotherapy development. This discovery earned him...

Susumu Tonegawa was a Japanese molecular biologist whose research fundamentally changed our understanding of the adaptive immune system. His work demonstrated that antibodies are not randomly produced but are encoded by specific genes within an individual’s DNA. This discovery revolutionized immunol...

Peter Medawar was a pioneering British biologist whose work fundamentally reshaped immunological understanding. His investigations into tissue rejection during organ transplantation demonstrated that acquired characteristics could be genetically inherited – a revolutionary concept challenging prevai...

John Macfarlane Burnet was a pioneering Australian virologist whose work fundamentally shaped immunology. His theory, developed throughout the 20th century, explains how the immune system identifies and responds to foreign invaders as distinct from the body's own cells. This groundbreaking research...

Immune Attack is an educational 3D video game created by the Federation of American Scientists’ Learning Technologies Program with Brown University and the University of Southern California, with support from the National Science Foundation. Players operate a small craft at the cellular and nanoscal...

Niels Jerne was a Danish immunologist whose groundbreaking work fundamentally reshaped our understanding of the adaptive immune system. His theories on self and non-self recognition, particularly the concept of antigen presentation, provided crucial insights into how the body learns to defend itself...