description John Najarian Overview
John Najarian was an American transplant surgeon whose career was closely associated with the University of Minnesota. He helped expand clinical kidney and liver transplantation and conducted work on immunosuppression, including the development and use of antilymphocyte globulin to reduce organ rejection. His work served patients requiring organ replacement and contributed to the development of transplantation as an established surgical specialty.
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What transplant work made John Najarian famous?
Najarian expanded kidney, liver and pancreas transplantation at the University of Minnesota. He also trained numerous transplant surgeons and helped make complex transplantation a sustained clinical programme.
What was Minnesota antilymphocyte globulin?
Minnesota antilymphocyte globulin, commonly called ALG, was an immune-suppressing preparation developed under Najarian's leadership. It was used to reduce organ rejection in transplant recipients.
Where did John Najarian lead transplant surgery?
He chaired the Department of Surgery at the University of Minnesota for decades. Minneapolis became a major centre for organ transplantation during his tenure.
Why was John Najarian's ALG programme controversial?
Federal authorities challenged the production and sale of Minnesota ALG, leading to a prominent criminal case against Najarian. He was acquitted of the principal charges, and an appeals court later criticised important aspects of the prosecution.
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