What enzyme did James B. Sumner successfully crystallize in 1926?

In 1926, James B. Sumner successfully isolated and crystallized the enzyme urease. He extracted this enzyme from jack beans, marking a massive breakthrough in biochemistry.

Why was James B. Sumner's crystallization of urease historically significant?

By isolating urease in crystalline form, Sumner provided definitive proof that enzymes are actually proteins. Prior to this breakthrough, the exact chemical nature of enzymes was heavily debated among scientists.

Did James B. Sumner receive a Nobel Prize for his biochemical research?

Yes, James B. Sumner was awarded the Nobel Prize in Chemistry in 1946. He shared the prize with John Howard Northrop and Wendell Meredith Stanley for their collective work on purifying and crystallizing enzymes.

Where did James B. Sumner conduct his famous enzyme research?

Sumner conducted his Nobel-winning research while working at Cornell University. Despite losing his left arm in a hunting accident early in his career, he built a highly successful laboratory there.

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James B. Sumner

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description James B. Sumner Overview

James B. Sumner (1887–1955) was an American chemist at Cornell University who, in 1926, crystallized the enzyme urease from jack beans. This was the first time an enzyme had been isolated in crystalline form, demonstrating that enzymes are proteins with defined structures. Sumner lost his left arm in a hunting accident at age 17 but continued his laboratory work.

He shared the 1946 Nobel Prize in Chemistry with John Howard Northrop and Wendell Meredith Stanley.

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How good is James B. Sumner?

James B. Sumner scores 7.72/10 (Good) on Lunoo, making it a well-rated option in the Chemist category. First enzyme crystallization was pivotal; Nobel recognition, though later biochemical advances overshadow broader reputation.

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See our alternatives page for James B. Sumner for a ranked list with scores. Top alternatives include: Robert B. Woodward, Dorothy Crowfoot Hodgkin, K. Barry Sharpless.

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Is James B. Sumner worth it in 2026?

With a score of 7.72/10, James B. Sumner is a solid option in Chemist. See all Chemist ranked.

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