description Allen Brain Atlas Overview
Developed by the Allen Institute for Brain Science, the Allen Brain Atlas refers to a family of digital research resources that connect brain anatomy with gene expression. Human and mouse datasets allow investigators to explore where particular genes are expressed in brain tissue. Anatomical reference material helps place those measurements within specific regions, linking molecular information to the organization of the brain. The resources support neuroscience and biomedical investigation, including work relevant to neurological disorders and fundamental brain function.
Different datasets cover particular species or developmental stages, so their scope needs to be checked before comparison. Gene expression describes the production of gene-derived molecules, not a direct recording of neurons firing. The atlas stands apart from a conventional illustrated anatomy book by offering searchable experimental data that researchers can examine alongside spatial information.
help Allen Brain Atlas FAQ
What is the Allen Brain Atlas used for in research?
It is used by neuroscientists to map and understand gene expression across the human and mouse brain. Created by the Allen Institute for Brain Science, it allows researchers to pinpoint exactly where specific genes are active, aiding in the study of neurological diseases.
Is the Allen Brain Atlas free to access for researchers?
Yes, the massive datasets generated by the Allen Institute are freely available to the public through their online portal. This open-science approach provides 3D anatomical and genetic data without requiring users to pay a subscription fee.
What is the difference between the Allen Mouse Brain Atlas and the Human Brain Atlas?
The Mouse Brain Atlas provides a highly detailed, cellular-resolution mapping of a normal adult mouse brain, which serves as a primary model for mammalian biology. The Human Brain Atlas focuses on human brain anatomy, utilizing MRI data and microarray data from post-mortem human tissue to map the cerebral cortex.
Who funds the creation of the Allen Brain Atlas?
The Allen Institute was founded in 2003 with a substantial initial seed donation of $100 million from Microsoft co-founder Paul G. Allen. It continues to be funded by the Paul G. Allen Frontiers Group, as well as government grants and private philanthropy.
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